Journal article
P. Mishra
2014
2014
Semantic Scholar
DOI
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APA
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Mishra, P. (2014). Is Mir-133a a Promising Therapeutic Target for Heart Failure?
Chicago/Turabian
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Mishra, P. “Is Mir-133a a Promising Therapeutic Target for Heart Failure?” (2014).
MLA
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Mishra, P. Is Mir-133a a Promising Therapeutic Target for Heart Failure? 2014.
BibTeX Click to copy
@article{p2014a,
title = {Is Mir-133a a Promising Therapeutic Target for Heart Failure?},
year = {2014},
author = {Mishra, P.}
}
Abstract
Although miR-133 mitigates cardiac hypertrophy and fibrosis, fine tunes β1-AR signaling, and protects against oxidative stress mediated apoptosis, it is unclear whether overexpression of miR-133a can ameliorate left ventricular function in failing hearts. Considering its multidisciplinary role in the heart, it is suggested that miR-133a is a master regulator of several networks that controls pathological cardiac remodeling. Therefore, it is a promising therapeutic target for heart failure.